Further experiments on the inhibition of aconitase by enzymically prepared fluorocitric acid
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چکیده
منابع مشابه
The synthesis of fluorocitric acid and its inhibition in acetate.
The theory that the citric acid formation induced by the poison fluoroacetate in vitro (Liebecq & Peters, 1949; Martius, 1949) and in vivo (Buffa & Peters, 1949) is due to the synthesis of a fluorotricarboxylic acid has been proved by the isolation ofa crystalline fluorocitric acid (Peters, Wakelin, Buffa & Thomas, 1953) and by the observation that this substance inhibits the enzyme aconitase i...
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15 صفحه اولInhibition of aconitase by trans-aconitate.
Bernheim (2), studying the properties of the “citric dehydrogenase” system, noted that aconitic acid (presumably the trans isomer) inhibited the reduction of methylene blue by citric acid. More recently, Morrison and Still (3), in a short report, claimed that truns-aconitic acid inhibited competitively the reaction cis-aconitate c citrate, catalyzed by the aconitase of rhubarb leaf. The present...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1961
ISSN: 0306-3283
DOI: 10.1042/bj0790261